iPTMnet Report for Q96N76 (UROC1)
Protein Information
| UniProt AC / UniProt ID | Q96N76 / HUTU_HUMAN |
| Protein Name | Urocanate hydratase |
| Gene Name | Name: UROC1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96N76 |
| PRO Name | urocanate hydratase (human) |
| Definition | A urocanate hydratase that is encoded in the genome of human. |
| Short Label | hUROC1 |
| Category | organism-gene |
Q96N76 (UROC1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S542 | O-Glycosylation | score1 | GlyGen | 35289036 | ||
| T612 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S253 | N253 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S388 | L388 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S388 | P388 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |
DAG View