iPTMnet Report for Q96N76 (UROC1)
Protein Information
UniProt AC / UniProt ID | Q96N76 / HUTU_HUMAN |
Protein Name | Urocanate hydratase |
Gene Name | Name: UROC1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96N76 |
PRO Name | urocanate hydratase (human) |
Definition | A urocanate hydratase that is encoded in the genome of human. |
Short Label | hUROC1 |
Category | organism-gene |
Q96N76 (UROC1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y185 | Phosphorylation | score1 | PhosphoSitePlus | |||
S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
S388 | Phosphorylation | score1 | PhosphoSitePlus | |||
S542 | O-Glycosylation | score1 | GlyGen | 35289036 | ||
T612 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S253 | N253 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S388 | L388 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S388 | P388 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |