iPTMnet Report for Q96N67 (DOCK7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96N67 / DOCK7_HUMAN
Protein Name Dedicator of cytokinesis protein 7
Gene Name Name: DOCK7
Synonyms:KIAA1771;
Organism Homo sapiens (Human)

PRO ID PR:Q96N67
DAG View
PRO Name dedicator of cytokinesis protein 7 (human)
Definition A dedicator of cytokinesis protein 7 that is encoded in the genome of human.
Short Label hDOCK7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96N67 (DOCK7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
S28 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S30 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
K133 Ubiquitination PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
S180 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S182 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T186 Phosphorylation PhosphoSitePlus
S190 O-Glycosylation GlyGen 32119511, 30379171, 34725712, ...28657654, 35254053
S190 Phosphorylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K381 Methylation PhosphoSitePlus   UniProt 24129315
K381 Ubiquitination PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
T450 Phosphorylation PhosphoSitePlus
T451 Phosphorylation PhosphoSitePlus
S452 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S497 Phosphorylation PhosphoSitePlus
Y522 Phosphorylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
T649 Phosphorylation PhosphoSitePlus
S864 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S873 Phosphorylation PhosphoSitePlus
Y876 Phosphorylation PhosphoSitePlus
T878 Phosphorylation PhosphoSitePlus
S882 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S888 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S894 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S896 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S898 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S900 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 18220336
S905 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T907 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
T909 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S910 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 19690332
S917 Phosphorylation PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
S929 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S946 Phosphorylation PhosphoSitePlus
S948 Phosphorylation PhosphoSitePlus
S958 Phosphorylation PhosphoSitePlus
S963 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
S964 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18220336
S969 Phosphorylation PhosphoSitePlus
T981 Phosphorylation PhosphoSitePlus
Y1242 Phosphorylation PhosphoSitePlus
Y1257 Phosphorylation P04626 (ERBB2) PhosphoSitePlus   Signor 18426980
T1296 Phosphorylation PhosphoSitePlus
S1297 Phosphorylation PhosphoSitePlus
T1302 Phosphorylation PhosphoSitePlus
S1306 Phosphorylation PhosphoSitePlus
Y1372 Phosphorylation PhosphoSitePlus
S1383 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
T1385 Phosphorylation PhosphoSitePlus
K1388 Methylation PhosphoSitePlus
K1390 Phosphorylation UniProt 18669648
A1394 Phosphorylation UniProt 18669648
E1398 Phosphorylation UniProt 17525332, 18669648
S1403 Phosphorylation PhosphoSitePlus
R1415 Methylation PhosphoSitePlus
Y1421 Phosphorylation PhosphoSitePlus   UniProt 18669648
T1422 Phosphorylation PhosphoSitePlus
S1425 Phosphorylation PhosphoSitePlus   UniProt 18669648
R1429 Phosphorylation UniProt 17525332, 18669648
S1430 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 18220336
S1432 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1434 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1438 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 33704464, 18669648, 23186163, ...19690332
K1446 Ubiquitination PhosphoSitePlus
T1455 Phosphorylation PhosphoSitePlus
S1874 Phosphorylation PhosphoSitePlus
K1962 Acetylation PhosphoSitePlus   UniProt 19608861
K1962 Methylation PhosphoSitePlus
T1991 Phosphorylation PhosphoSitePlus
K2003 Ubiquitination PhosphoSitePlus
K2080 Ubiquitination PhosphoSitePlus
K2088 Ubiquitination PhosphoSitePlus
K2112 Ubiquitination PhosphoSitePlus
Y2117 Phosphorylation PhosphoSitePlus
T2124 Phosphorylation PhosphoSitePlus
S2129 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2131 Phosphorylation PhosphoSitePlus
S2134 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y27 Phosphorylation PhosphoSitePlus
S28 Phosphorylation phospho.ELM 18669648
S30 Phosphorylation phospho.ELM 18669648
S180 Phosphorylation phospho.ELM 18669648
S182 Phosphorylation phospho.ELM 18669648
T186 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S452 Phosphorylation phospho.ELM 18669648
S864 Phosphorylation phospho.ELM 18669648
S882 Phosphorylation phospho.ELM 18669648
S888 Phosphorylation phospho.ELM 18669648
S894 Phosphorylation phospho.ELM 18669648
S896 Phosphorylation phospho.ELM 18669648
S898 Phosphorylation phospho.ELM 18669648
S900 Phosphorylation phospho.ELM 18669648, 18220336
S905 Phosphorylation phospho.ELM 18669648
T907 Phosphorylation phospho.ELM 18669648
T909 Phosphorylation phospho.ELM 18669648
S910 Phosphorylation phospho.ELM 18669648
S929 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S963 Phosphorylation phospho.ELM 18669648, 18220336
S964 Phosphorylation phospho.ELM 18669648, 18220336
T1296 Phosphorylation PhosphoSitePlus
S1297 Phosphorylation PhosphoSitePlus
S1306 Phosphorylation PhosphoSitePlus
S1383 Phosphorylation phospho.ELM 18669648
S1421 Phosphorylation PhosphoSitePlus
S1423 Phosphorylation PhosphoSitePlus
S1425 Phosphorylation PhosphoSitePlus
S1429 Phosphorylation PhosphoSitePlus
K1951 Acetylation PhosphoSitePlus
S2123 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y27 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S917 Phosphorylation PhosphoSitePlus
S921 Phosphorylation PhosphoSitePlus
K922 Ubiquitination PhosphoSitePlus
S932 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus
T1265 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
S1275 Phosphorylation PhosphoSitePlus
S1390 Phosphorylation PhosphoSitePlus
S1392 Phosphorylation PhosphoSitePlus
S1394 Phosphorylation PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
K1922 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation HPRD 19413330, 18669648, 20068231
S30 Phosphorylation HPRD 19413330, 18669648, 19691289, ...20068231, 17924679
S180 Phosphorylation HPRD 19413330, 19664994, 19007248, ...19691289, 18669648, 20068231
S182 Phosphorylation HPRD 19413330, 18669648, 20068231
S452 Phosphorylation HPRD 18669648, 20068231
S863 Phosphorylation HPRD 20068231
S864 Phosphorylation HPRD 18669648, 20068231
S882 Phosphorylation HPRD 18669648
S888 Phosphorylation HPRD 18669648, 19664994
S894 Phosphorylation HPRD 19413330, 18669648
S896 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
S898 Phosphorylation HPRD 19413330, 18669648
S900 Phosphorylation HPRD 19413330, 20058876, 19664994, ...19664995, 18452278, 18669648, 20166139, 19415658, 20068231
S905 Phosphorylation HPRD 18669648
T907 Phosphorylation HPRD 19413330, 18669648
T909 Phosphorylation HPRD 19413330, 18669648
S910 Phosphorylation HPRD 19413330, 18669648
S932 Phosphorylation HPRD 18669648, 20068231
S933 Phosphorylation HPRD 18669648, 20068231
S1275 Phosphorylation HPRD 19664994, 19691289
S1352 Phosphorylation HPRD 19413330, 18767875, 19664994, ...19691289, 17322306, 18669648, 20068231
T1354 Phosphorylation HPRD 19007248, 20068231
S1399 Phosphorylation HPRD 19413330, 19691289, 20068231
S1401 Phosphorylation HPRD 19413330, 20058876, 19664995, ...19691289, 18669648, 20068231
S1407 Phosphorylation HPRD 19413330, 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S180 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S190 N190 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K199 Q199 Biomuta DOID:1612 / breast cancer [ cosmic ]
K381 N381 Biomuta DOID:4159 / skin cancer [ cosmic ]
S432 Y432 Biomuta [ cosmic ]
S432 P432 Biomuta DOID:363 / uterine cancer [ cosmic ]
S452 N452 Biomuta DOID:3571 / liver cancer [ cosmic ]
T649 A649 Biomuta DOID:263 / kidney cancer [ cosmic ]
S873 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y876 F876 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S905 Y905 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T907 S907 Biomuta DOID:1324 / lung cancer [ cosmic ]
S921 R921 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K922 T922 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S932 Y932 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S963 Y963 Biomuta DOID:9256 / colorectal cancer [ cosmic, cosmic ] DOID:1612 / breast cancer [ cosmic, cosmic ] DOID:3571 / liver cancer [ cosmic ]
S1266 L1266 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1297 L1297 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1352 I1352 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc, cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S1383 I1383 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y1421 H1421 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1429 I1429 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1991 K1991 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y2117 H2117 Biomuta DOID:3571 / liver cancer [ cosmic ]