iPTMnet Report for Q96N46 (TTC14)
Protein Information
| UniProt AC / UniProt ID | Q96N46 / TTC14_HUMAN |
| Protein Name | Tetratricopeptide repeat protein 14 |
| Gene Name | Name: TTC14 Synonyms:KIAA1980;ORFNames:UNQ5813/PRO19630; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96N46 |
| PRO Name | tetratricopeptide repeat protein 14 (human) |
| Definition | A tetratricopeptide repeat protein 14 that is encoded in the genome of human. |
| Short Label | hTTC14 |
| Category | organism-gene |
Q96N46 (TTC14) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S33 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K66 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K71 | Acetylation | score1 | PhosphoSitePlus | |||
| S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R282 | Methylation | score1 | PhosphoSitePlus | |||
| K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K319 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K332 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K354 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K359 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K407 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K416 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K449 | Acetylation | score1 | PhosphoSitePlus | |||
| T453 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S454 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K460 | Acetylation | score1 | PhosphoSitePlus | |||
| K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K463 | Sumoylation | score1 | PhosphoSitePlus | |||
| T476 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S477 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S479 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S480 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S482 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S487 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S489 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S493 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S494 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S496 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S497 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S510 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S516 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S525 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K568 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S629 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y642 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S669 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T670 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S671 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
| S681 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S691 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T724 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S733 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S740 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| S741 | O-Glycosylation | score1 | GlyGen | 30379171 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S150 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S225 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y232 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T453 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S580 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S629 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S669 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T670 | Phosphorylation | score0 | HPRD | 18691976, 20068231 | ||
| S671 | Phosphorylation | score0 | HPRD | 18691976, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S150 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S225 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y232 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y428 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y434 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S150 | N150 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y232 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R282 | K282 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K332 | E332 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S480 | C480 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S487 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S494 | F494 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K568 | N568 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S629 | F629 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y642 | N642 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T670 | I670 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View