iPTMnet Report for Q96MT8 (CEP63)
Protein Information
| UniProt AC / UniProt ID | Q96MT8 / CEP63_HUMAN |
| Protein Name | Centrosomal protein of 63 kDa |
| Gene Name | Name: CEP63 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96MT8 |
| PRO Name | centrosomal protein of 63 kDa (human) |
| Definition | A centrosomal protein of 63 kDa that is encoded in the genome of human. |
| Short Label | hCEP63 |
| Category | organism-gene |
Q96MT8 (CEP63) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 22814378 | ||
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K62 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K269 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S278 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K389 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K396 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K435 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K470 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K508 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T576 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S586 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S650 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S653 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S657 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K689 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S495 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K319 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S445 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S449 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K298 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K319 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K145 | E145 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K269 | N269 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K298 | N298 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| S449 | F449 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
| S495 | F495 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S657 | F657 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
DAG View