iPTMnet Report for Q96MT3 (PRICKLE1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96MT3 / PRIC1_HUMAN
Protein Name Prickle-like protein 1 precursor
Gene Name Name: PRICKLE1
Synonyms:RILP;
Organism Homo sapiens (Human)

PRO ID PR:Q96MT3
DAG View
PRO Name prickle-like protein 1 (human)
Definition A prickle-like protein 1 that is encoded in the genome of human.
Short Label hPRICKLE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96MT3 (PRICKLE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
T370 Phosphorylation Q8N4C8 (MINK1) neXtProt   PhosphoSitePlus 22037766
S379 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
N544 N-Glycosylation GlyGen 29671580
S597 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
T691 Phosphorylation PhosphoSitePlus
K711 Ubiquitination PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N544 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S353 L353 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S379 N379 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S451 R451 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S451 N451 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S451 G451 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S600 L600 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S653 R653 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S668 A668 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S683 F683 Biomuta DOID:1612 / breast cancer [ cosmic ]
K711 T711 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:263 / kidney cancer [ cosmic, icgc ]