iPTMnet Report for Q96MN2 (NLRP4)
Protein Information
UniProt AC / UniProt ID | Q96MN2 / NALP4_HUMAN |
Protein Name | NACHT, LRR and PYD domains-containing protein 4 |
Gene Name | Name: NLRP4 Synonyms:NALP4,PAN2,PYPAF4,RNH2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96MN2 |
PRO Name | NACHT, LRR and PYD domains-containing protein 4 (human) |
Definition | A NACHT, LRR and PYD domains-containing protein 4 that is encoded in the genome of human. |
Short Label | hNLRP4 |
Category | organism-gene |
Q96MN2 (NLRP4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T93 | Phosphorylation | score1 | IEDB | 32387766 | ||
K601 | Ubiquitination | score1 | PhosphoSitePlus | |||
S605 | Phosphorylation | score1 | PhosphoSitePlus | |||
K611 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S605 | F605 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
K611 | T611 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ] | |
K611 | M611 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |