iPTMnet Report for Q96MN2 (NLRP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96MN2 / NALP4_HUMAN
Protein Name NACHT, LRR and PYD domains-containing protein 4
Gene Name Name: NLRP4
Synonyms:NALP4,PAN2,PYPAF4,RNH2;
Organism Homo sapiens (Human)

PRO ID PR:Q96MN2
DAG View
PRO Name NACHT, LRR and PYD domains-containing protein 4 (human)
Definition A NACHT, LRR and PYD domains-containing protein 4 that is encoded in the genome of human.
Short Label hNLRP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96MN2 (NLRP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T93 Phosphorylation IEDB 32387766
K601 Ubiquitination PhosphoSitePlus
S605 Phosphorylation PhosphoSitePlus
K611 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S605 F605 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K611 T611 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:4606 / bile duct cancer [ cosmic ]
K611 M611 Biomuta DOID:3571 / liver cancer [ cosmic ]