Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96MG8 / PCMD1_HUMAN
Protein Name Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
Gene Name Name: PCMTD1
Organism Homo sapiens (Human)

PRO ID PR:Q96MG8
DAG View
PRO Name protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (human)
Definition A protein-L-isoaspartate O-methyltransferase domain-containing protein 1 that is encoded in the genome of human.
Short Label hPCMTD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96MG8 (PCMTD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25807930
K19 Ubiquitination PhosphoSitePlus
Y41 Phosphorylation PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y41 H41 Biomuta DOID:1909 / melanoma [ cosmic ]
Y46 H46 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:5041 / esophageal cancer [ tcga ]
Y46 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y51 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K52 T52 Biomuta DOID:363 / uterine cancer [ tcga ]
K209 E209 Biomuta DOID:1324 / lung cancer [ cosmic ]
S302 R302 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]