iPTMnet Report for Q96MG8 (PCMTD1)
Protein Information
UniProt AC / UniProt ID | Q96MG8 / PCMD1_HUMAN |
Protein Name | Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 |
Gene Name | Name: PCMTD1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96MG8 |
PRO Name | protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (human) |
Definition | A protein-L-isoaspartate O-methyltransferase domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hPCMTD1 |
Category | organism-gene |
Q96MG8 (PCMTD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
G2 | Myristoylation | score1 | UniProt | 25807930 | ||
K19 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y41 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y42 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y46 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y51 | Phosphorylation | score1 | PhosphoSitePlus | |||
K52 | Ubiquitination | score1 | PhosphoSitePlus | |||
K124 | Ubiquitination | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
S302 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y41 | H41 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
Y46 | H46 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y51 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K209 | E209 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S302 | R302 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |