iPTMnet Report for Q96MG7 (NSMCE3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96MG7 / NSE3_HUMAN
Protein Name Non-structural maintenance of chromosomes element 3 homolog
Gene Name Name: NSMCE3
Synonyms:HCA4,MAGEG1,NDNL2;
Organism Homo sapiens (Human)

PRO ID PR:Q96MG7
DAG View
PRO Name non-structural maintenance of chromosomes element 3 homolog (human)
Definition A non-structural maintenance of chromosomes element 3 homolog that is encoded in the genome of human.
Short Label hNSMCE3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96MG7 (NSMCE3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S49 Phosphorylation PhosphoSitePlus
S51 Phosphorylation HPRD   PhosphoSitePlus 20068231
S57 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18077418, 17525332, 23186163, ...18669648
S60 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 22067460, 17525332, 23186163, ...19664995
S64 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 19664995, ...22067460, 18669648, 24275569, 20068231, 20068230
K83 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
K260 Acetylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
S298 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S304 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 22067460, 18669648, 15302935


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S49 I49 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S60 W60 Biomuta DOID:1612 / breast cancer [ cosmic ]
K194 M194 Biomuta DOID:263 / kidney cancer [ cosmic ]
K211 N211 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K260 N260 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]