iPTMnet Report for Q96ME1 (FBXL18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96ME1 / FXL18_HUMAN
Protein Name F-box/LRR-repeat protein 18
Gene Name Name: FBXL18
Synonyms:FBL18;
Organism Homo sapiens (Human)

PRO ID PR:Q96ME1
DAG View
PRO Name F-box/LRR-repeat protein 18 (human)
Definition An F-box/LRR-repeat protein 18 that is encoded in the genome of human.
Short Label hFBXL18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96ME1 (FBXL18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K76 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
R446 Methylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
T650 Phosphorylation PhosphoSitePlus
S653 Phosphorylation PhosphoSitePlus
K706 Methylation PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K138 E138 Biomuta DOID:1324 / lung cancer [ cosmic ]
K299 T299 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R446 C446 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S472 P472 Biomuta DOID:1612 / breast cancer [ icgc ]