iPTMnet Report for Q96M94 (KLHL15)
Protein Information
| UniProt AC / UniProt ID | Q96M94 / KLH15_HUMAN |
| Protein Name | Kelch-like protein 15 |
| Gene Name | Name: KLHL15 Synonyms:KIAA1677; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96M94 |
| PRO Name | kelch-like protein 15 (human) |
| Definition | A kelch-like protein 15 that is encoded in the genome of human. |
| Short Label | hKLHL15 |
| Category | organism-gene |
Q96M94 (KLHL15) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T217 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S366 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K405 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C467 | Methylation | score1 | IEDB | 31844290 | ||
| K471 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K473 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K581 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K271 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S358 | F358 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
| C467 | Y467 | Biomuta | DOID:3565 / meningioma [ cosmic ] | |
| K473 | T473 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K473 | N473 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View