iPTMnet Report for Q96M69 (LRGUK)
Protein Information
| UniProt AC / UniProt ID | Q96M69 / LRGUK_HUMAN |
| Protein Name | Leucine-rich repeat and guanylate kinase domain-containing protein |
| Gene Name | Name: LRGUK |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96M69 |
| PRO Name | leucine-rich repeat and guanylate kinase domain-containing protein (human) |
| Definition | A leucine-rich repeat and guanylate kinase domain-containing protein that is encoded in the genome of human. |
| Short Label | hLRGUK |
| Category | organism-gene |
Q96M69 (LRGUK) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y322 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
| Y529 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y540 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y543 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S560 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S15 | T15 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| Y322 | C322 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S560 | Y560 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View