iPTMnet Report for Q96M02 (C10orf90)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96M02 / CJ090_HUMAN
Protein Name (E2-independent) E3 ubiquitin-conjugating enzyme FATS
Gene Name Name: C10orf90
Synonyms:FATS;
Organism Homo sapiens (Human)

PRO ID PR:Q96M02
DAG View
PRO Name (E2-independent) E3 ubiquitin-conjugating enzyme FATS (human)
Definition An (E2-independent) E3 ubiquitin-conjugating enzyme FATS that is encoded in the genome of human.
Short Label hC10orf90
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96M02 (C10orf90) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y222 Phosphorylation PhosphoSitePlus
T232 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
T620 Phosphorylation PhosphoSitePlus
T626 Phosphorylation PhosphoSitePlus
K639 Acetylation PhosphoSitePlus
S644 O-Glycosylation GlyGen 30379171
S652 Phosphorylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
Y656 Phosphorylation PhosphoSitePlus
K663 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y222 H222 Biomuta DOID:363 / uterine cancer [ icgc ]
Y222 C222 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S270 Y270 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S270 P270 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K418 N418 Biomuta DOID:363 / uterine cancer [ icgc ]
K418 E418 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T534 A534 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T626 K626 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T626 M626 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]