iPTMnet Report for Q96LR5 (UBE2E2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96LR5 / UB2E2_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 E2
Gene Name Name: UBE2E2
Synonyms:UBCH8;
Organism Homo sapiens (Human)

PRO ID PR:Q96LR5
DAG View
PRO Name ubiquitin-conjugating enzyme E2 E2 (human)
Definition A ubiquitin-conjugating enzyme E2 E2 that is encoded in the genome of human.
Short Label hUBE2E2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96LR5 (UBE2E2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
T3 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus   UniProt 24275569
S15 Phosphorylation PhosphoSitePlus   UniProt 24275569
S18 Phosphorylation PhosphoSitePlus   UniProt 24275569
S19 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692
K44 Methylation PhosphoSitePlus
K48 Acetylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K52 Acetylation PhosphoSitePlus
K52 Methylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 G18 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K48 T48 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T49 I49 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S54 * Biomuta DOID:4159 / skin cancer [ cosmic ]