iPTMnet Report for Q96LC7 (SIGLEC10)
Protein Information
| UniProt AC / UniProt ID | Q96LC7 / SIG10_HUMAN |
| Protein Name | Sialic acid-binding Ig-like lectin 10 precursor |
| Gene Name | Name: SIGLEC10 Synonyms:SLG2;ORFNames:UNQ477/PRO940; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96LC7 |
| PRO Name | sialic acid-binding Ig-like lectin 10 (human) |
| Definition | A sialic acid-binding Ig-like lectin 10 that is encoded in the genome of human. |
| Short Label | hSIGLEC10 |
| Category | organism-gene |
DAG ViewQ96LC7 (SIGLEC10) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N100 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T322 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N355 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N361 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N364 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S589 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S592 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T593 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y597 | Phosphorylation | P52333 (JAK3) , Q08881 (ITK) , P06239 (LCK) | score3 | neXtProt phospho.ELM PhosphoSitePlus Signor | 11733002 | |
| S630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y667 | Phosphorylation | Q08881 (ITK) , P52333 (JAK3) , P06239 (LCK) , P06241 (FYN) | score4 | IntAct neXtProt phospho.ELM PhosphoSitePlus Signor UniProt | 11733002, 12163025 | |
| Y691 | Phosphorylation | P52333 (JAK3) , P06239 (LCK) | score3 | phospho.ELM PhosphoSitePlus Signor | 11733002 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S9 | L9 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S38 | A38 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T250 | M250 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
| S298 | Y298 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| N355 | K355 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| N364 | K364 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T593 | M593 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y597 | C597 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
