iPTMnet Report for Q96L92 (SNX27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96L92 / SNX27_HUMAN
Protein Name Sorting nexin-27
Gene Name Name: SNX27
Synonyms:KIAA0488;ORFNames:My014;
Organism Homo sapiens (Human)

PRO ID PR:Q96L92
DAG View
PRO Name sorting nexin-27 (human)
Definition A sorting nexin-27 that is encoded in the genome of human.
Short Label hSNX27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96L92 (SNX27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus   UniProt 23186163
S62 Phosphorylation PhosphoSitePlus   UniProt 20068231
S69 Phosphorylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
R218 Methylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
T297 Phosphorylation PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
Y346 Phosphorylation PhosphoSitePlus
C354 Methylation IEDB 31844290
Y392 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
Y400 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
C432 Methylation IEDB 31844290
T504 Phosphorylation PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S51 Phosphorylation HPRD 19664994
S62 Phosphorylation HPRD 20068231
Y392 Phosphorylation HPRD 17322306
T504 Phosphorylation HPRD 20068231
Y506 Phosphorylation HPRD 20068231
Y528 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q12879 (GRIN2A) S1459 Q96L92 (SNX27) increased_association eFIP 34233182


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y75 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R218 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
C432 F432 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y506 C506 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K522 R522 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]