iPTMnet Report for Q96L50 (LRR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96L50 / LLR1_HUMAN
Protein Name Leucine-rich repeat protein 1
Gene Name Name: LRR1
Synonyms:PPIL5;
Organism Homo sapiens (Human)

PRO ID PR:Q96L50
DAG View
PRO Name leucine-rich repeat protein 1 (human)
Definition A peptidylprolyl isomerase-like 5 that is encoded in the genome of human.
Short Label hLRR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96L50 (LRR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C5 Methylation IEDB 31844290
S31 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
C91 Methylation IEDB 31844290
K94 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K235 Acetylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K78 N78 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K84 T84 Biomuta DOID:4159 / skin cancer [ cosmic ]
K84 N84 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K94 E94 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T128 S128 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T136 A136 Biomuta DOID:1324 / lung cancer [ cosmic ]
K239 Q239 Biomuta DOID:3571 / liver cancer [ cosmic ]
K252 T252 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K283 * Biomuta DOID:3571 / liver cancer [ cosmic ]