iPTMnet Report for Q96L42 (KCNH8)
Protein Information
| UniProt AC / UniProt ID | Q96L42 / KCNH8_HUMAN |
| Protein Name | Potassium voltage-gated channel subfamily H member 8 |
| Gene Name | Name: KCNH8 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96L42 |
| PRO Name | potassium voltage-gated channel subfamily H member 8 (human) |
| Definition | A voltage-gated potassium channel KCNH8 that is encoded in the genome of human. |
| Short Label | hKCNH8 |
| Category | organism-gene |
Q96L42 (KCNH8) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K626 | Acetylation | score1 | PhosphoSitePlus | |||
| K632 | Acetylation | score1 | PhosphoSitePlus | |||
| K776 | Acetylation | score1 | PhosphoSitePlus | |||
| K864 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S1048 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S205 | F205 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K626 | N626 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K632 | N632 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| K776 | N776 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K864 | N864 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K864 | E864 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S1048 | N1048 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
| S1048 | R1048 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View