iPTMnet Report for Q96KG9 (SCYL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96KG9 / SCYL1_HUMAN
Protein Name N-terminal kinase-like protein
Gene Name Name: SCYL1
Synonyms:CVAK90,GKLP,NTKL,TAPK,TEIF,TRAP;ORFNames:HT019;
Organism Homo sapiens (Human)

PRO ID PR:Q96KG9
DAG View
PRO Name N-terminal kinase-like protein (human)
Definition An N-terminal kinase-like protein that is encoded in the genome of human.
Short Label hSCYL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96KG9 (SCYL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus   Signor 24769208
T469 Phosphorylation P31749 (AKT1) Signor 24769208
K536 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
T640 Phosphorylation PhosphoSitePlus
S676 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
Y725 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
T741 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
S754 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 35948564, 17081983, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S558 Phosphorylation HPRD 17322306
S568 Phosphorylation HPRD 20068231
S681 Phosphorylation HPRD 20068231
S754 Phosphorylation HPRD 19651622, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S558 Phosphorylation HPRD 17322306
S568 Phosphorylation HPRD 20068231
T603 Phosphorylation PhosphoSitePlus
S664 Phosphorylation HPRD 20068231
S737 Phosphorylation HPRD 19651622, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K292 R292 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K292 T292 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S559 N559 Biomuta DOID:4159 / skin cancer [ cosmic ]
T603 M603 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
T603 A603 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S732 F732 Biomuta DOID:1324 / lung cancer [ cosmic ]
S737 Y737 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S754 Y754 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]