iPTMnet Report for Q96KG7 (MEGF10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96KG7 / MEG10_HUMAN
Protein Name Multiple epidermal growth factor-like domains protein 10 precursor
Gene Name Name: MEGF10
Synonyms:KIAA1780;
Organism Homo sapiens (Human)

PRO ID PR:Q96KG7
DAG View
PRO Name multiple epidermal growth factor-like domains protein 10 (human)
Definition A multiple epidermal growth factor-like domains protein 10 that is encoded in the genome of human.
Short Label hMEGF10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96KG7 (MEGF10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N580 N-Glycosylation GlyGen 23090970, 24190977
N678 N-Glycosylation GlyGen 23090970, 24190977
Y751 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
T775 Phosphorylation PhosphoSitePlus
N807 N-Glycosylation GlyGen 23090970, 24190977
S888 Phosphorylation PhosphoSitePlus
Y895 Phosphorylation PhosphoSitePlus
T979 Phosphorylation PhosphoSitePlus
Y989 Phosphorylation PhosphoSitePlus
K1005 Ubiquitination PhosphoSitePlus
S1006 Phosphorylation PhosphoSitePlus
K1008 Ubiquitination PhosphoSitePlus
Y1016 Phosphorylation PhosphoSitePlus
Y1030 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23954233
Y1030 Phosphorylation P12931 (SRC) PhosphoSitePlus 23954233
Y1048 Phosphorylation PhosphoSitePlus
Y1061 Phosphorylation PhosphoSitePlus
Y1075 Phosphorylation PhosphoSitePlus
Y1099 Phosphorylation PhosphoSitePlus
Y1111 Phosphorylation PhosphoSitePlus
S1128 Phosphorylation PhosphoSitePlus
S1133 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1082 Phosphorylation HPRD 18767875
S1089 Phosphorylation HPRD 18767875
Y1099 Phosphorylation HPRD 18767875


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N580 T580 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
N678 D678 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S771 F771 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
N807 T807 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S888 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K1008 N1008 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y1030 C1030 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1082 G1082 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1089 N1089 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1128 T1128 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]