iPTMnet Report for Q96K76 (USP47)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96K76 / UBP47_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 47
Gene Name Name: USP47
Organism Homo sapiens (Human)

PRO ID PR:Q96K76
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 47 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 47 that is encoded in the genome of human.
Short Label hUSP47
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96K76 (USP47) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K121 Ubiquitination PhosphoSitePlus
K122 Acetylation PhosphoSitePlus   UniProt 19608861
K122 Ubiquitination PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S165 Phosphorylation phospho.ELM 18669648
T166 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
Y384 Phosphorylation PhosphoSitePlus
T387 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
K404 Acetylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
Y487 Phosphorylation PhosphoSitePlus
Y504 Phosphorylation PhosphoSitePlus
Y505 Phosphorylation PhosphoSitePlus
T528 Phosphorylation PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus
Y546 Phosphorylation PhosphoSitePlus
Y557 Phosphorylation PhosphoSitePlus
Y561 Phosphorylation PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K583 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
T743 Phosphorylation PhosphoSitePlus
K779 Acetylation PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
K782 Ubiquitination PhosphoSitePlus
R817 Methylation PhosphoSitePlus
S832 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
S835 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y836 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S837 Phosphorylation PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K844 Ubiquitination PhosphoSitePlus
C856 S-Nitrosylation dbSNO 26338901
K860 Ubiquitination PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
K867 Ubiquitination PhosphoSitePlus
S868 Phosphorylation PhosphoSitePlus
S876 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T877 Phosphorylation phospho.ELM 18669648
K881 Ubiquitination PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
S910 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 18669648, ...19690332, 20068231
S917 Phosphorylation phospho.ELM 18669648
S918 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T932 Phosphorylation PhosphoSitePlus
S933 Phosphorylation PhosphoSitePlus   UniProt 23186163
S944 Phosphorylation PhosphoSitePlus
S946 Phosphorylation PhosphoSitePlus
T1005 Phosphorylation PhosphoSitePlus
T1008 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1015 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1017 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1022 Phosphorylation PhosphoSitePlus
S1025 Phosphorylation PhosphoSitePlus
K1058 Ubiquitination PhosphoSitePlus
S1088 Phosphorylation PhosphoSitePlus
S1103 O-Glycosylation GlyGen 23301498, 29351928
S1105 O-Glycosylation GlyGen 23301498, 29351928
Y1123 Phosphorylation PhosphoSitePlus
K1156 Ubiquitination PhosphoSitePlus
S1221 Phosphorylation PhosphoSitePlus
S1223 Phosphorylation PhosphoSitePlus
K1258 Ubiquitination PhosphoSitePlus
K1274 Ubiquitination PhosphoSitePlus
T1321 Phosphorylation PhosphoSitePlus
K1337 Acetylation PhosphoSitePlus
S1340 Phosphorylation PhosphoSitePlus
S1341 Phosphorylation PhosphoSitePlus
Y1352 Phosphorylation PhosphoSitePlus
S1353 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18088087
Y1363 Phosphorylation PhosphoSitePlus
T1373 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T440 Phosphorylation HPRD 19664994
S744 Phosphorylation HPRD 17322306, 19651622, 18669648, ...16964243, 20068231
S747 Phosphorylation HPRD 18669648
Y748 Phosphorylation HPRD 18691976, 18669648
S788 Phosphorylation HPRD 18669648
T789 Phosphorylation HPRD 18669648
S822 Phosphorylation HPRD 17322306, 18767875, 19664994, ...19651622, 18669648, 20068231
S829 Phosphorylation HPRD 18669648
S830 Phosphorylation HPRD 18669648
T844 Phosphorylation HPRD 19651622
S845 Phosphorylation HPRD 19651622, 20068231
S925 Phosphorylation HPRD 19651622, 18452278
T927 Phosphorylation HPRD 19651622
S929 Phosphorylation HPRD 19651622
S1133 Phosphorylation HPRD 20068231
S1135 Phosphorylation HPRD 20068231
T1233 Phosphorylation HPRD 20068231
Y1264 Phosphorylation HPRD 20068231
S1265 Phosphorylation HPRD 18669648, 18088087, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S162 Y162 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y504 * Biomuta DOID:363 / uterine cancer [ cosmic ]
Y504 H504 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y561 C561 Biomuta DOID:3571 / liver cancer [ cosmic ]
S744 F744 Biomuta [ cosmic ]
Y748 H748 Biomuta DOID:1324 / lung cancer [ cosmic ]
T780 P780 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R817 W817 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S832 F832 Biomuta [ cosmic ]
Y836 H836 Biomuta DOID:1324 / lung cancer [ cosmic ]
S896 N896 Biomuta DOID:1319 / brain cancer [ cosmic ]
S897 I897 Biomuta DOID:1612 / breast cancer [ cosmic ]
S925 Y925 Biomuta DOID:363 / uterine cancer [ icgc ]
S946 L946 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1013 Y1013 Biomuta DOID:363 / uterine cancer [ icgc ]
K1258 T1258 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K1274 R1274 Biomuta DOID:4362 / cervical cancer [ cosmic ]