iPTMnet Report for Q96K49 (TMEM87B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96K49 / TM87B_HUMAN
Protein Name Transmembrane protein 87B precursor
Gene Name Name: TMEM87B
Organism Homo sapiens (Human)

PRO ID PR:Q96K49
DAG View
PRO Name transmembrane protein 87B (human)
Definition A transmembrane protein 87B that is encoded in the genome of human.
Short Label hTMEM87B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96K49 (TMEM87B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N68 N-Glycosylation GlyGen 29741879, 24190977
K111 Ubiquitination PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
N159 N-Glycosylation GlyGen 24190977
N162 N-Glycosylation GlyGen 24190977
S268 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus   UniProt 19690332
S494 Phosphorylation PhosphoSitePlus   UniProt 21406692
S496 Phosphorylation PhosphoSitePlus   UniProt 21406692
T499 Phosphorylation PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
T504 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231, 24275569
K547 Ubiquitination PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S534 Phosphorylation HPRD 20058876, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S274 R274 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S496 C496 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K501 N501 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K547 R547 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S550 Y550 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]