iPTMnet Report for Q96JP0 (FEM1C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96JP0 / FEM1C_HUMAN
Protein Name Protein fem-1 homolog C
Gene Name Name: FEM1C
Synonyms:KIAA1785;
Organism Homo sapiens (Human)

PRO ID PR:Q96JP0
DAG View
PRO Name protein fem-1 homolog C (human)
Definition A protein fem-1 homolog C that is encoded in the genome of human.
Short Label hFEM1C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96JP0 (FEM1C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K4 Ubiquitination PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
Y363 Phosphorylation PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
N439 N-Glycosylation GlyGen 24190977
C450 Methylation IEDB 31844290
Y470 Phosphorylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
T494 Phosphorylation PhosphoSitePlus
C503 Methylation IEDB 31844290
K561 Ubiquitination PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K28 E28 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K28 R28 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y268 * Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
S333 F333 Biomuta DOID:4159 / skin cancer [ cosmic ]
K561 R561 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K571 E571 Biomuta DOID:9256 / colorectal cancer [ cosmic ]