iPTMnet Report for Q96JM7 (L3MBTL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96JM7 / LMBL3_HUMAN
Protein Name Lethal(3)malignant brain tumor-like protein 3
Gene Name Name: L3MBTL3
Synonyms:KIAA1798,MBT1;
Organism Homo sapiens (Human)

PRO ID PR:Q96JM7
DAG View
PRO Name lethal(3)malignant brain tumor-like protein 3 (human)
Definition A lethal(3)malignant brain tumor-like protein 3 that is encoded in the genome of human.
Short Label hL3MBTL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96JM7 (L3MBTL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S170 Phosphorylation PhosphoSitePlus
K180 Sumoylation PhosphoSitePlus
K197 Sumoylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
K336 Sumoylation PhosphoSitePlus
K376 Sumoylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
K480 Sumoylation PhosphoSitePlus
K486 Acetylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 19690332, ...24275569
S610 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
S625 Phosphorylation PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
C682 Methylation IEDB 31844290
S691 Phosphorylation PhosphoSitePlus
K692 Ubiquitination PhosphoSitePlus
K704 Sumoylation PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S608 Phosphorylation HPRD 19413330, 19664995, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S583 Phosphorylation HPRD 19413330, 19664995, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S170 G170 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K197 I197 Biomuta DOID:4159 / skin cancer [ cosmic ]
S206 L206 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S217 L217 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K336 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K376 Q376 Biomuta DOID:363 / uterine cancer [ icgc ]
T435 P435 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S601 I601 Biomuta DOID:1324 / lung cancer [ cosmic ]
S623 F623 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S625 F625 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S675 F675 Biomuta DOID:4159 / skin cancer [ cosmic ]