iPTMnet Report for Q96JK2 (DCAF5)
Protein Information
| UniProt AC / UniProt ID | Q96JK2 / DCAF5_HUMAN |
| Protein Name | DDB1- and CUL4-associated factor 5 |
| Gene Name | Name: DCAF5 Synonyms:BCRG2,KIAA1824,WDR22; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96JK2 |
| PRO Name | DDB1- and CUL4-associated factor 5 (human) |
| Definition | A DDB1- and CUL4-associated factor 5 that is encoded in the genome of human. |
| Short Label | hDCAF5 |
| Category | organism-gene |
Q96JK2 (DCAF5) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y260 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K364 | Methylation | score1 | PhosphoSitePlus | |||
| K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C382 | Methylation | score1 | IEDB | 31844290 | ||
| S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S476 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S496 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T497 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T500 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S552 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S561 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S562 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S563 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S564 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S568 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S580 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T581 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K604 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y615 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S626 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S628 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T630 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S631 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S632 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S638 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S645 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S648 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332, 24275569 | ||
| S651 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| S655 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K665 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K678 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K699 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K708 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S794 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S860 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S861 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S865 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T867 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S917 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K920 | Acetylation | score1 | PhosphoSitePlus | |||
| T929 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S931 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K92 | N92 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S264 | F264 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K364 | T364 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S468 | F468 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S568 | A568 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] | |
| S628 | F628 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S631 | L631 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S651 | Y651 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K699 | Q699 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K708 | N708 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S865 | L865 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T867 | A867 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T867 | I867 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T929 | K929 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |
DAG View