Protein Information

Cytoscape View

UniProt AC / UniProt ID Q96JJ3 / ELMO2_HUMAN
Protein Name Engulfment and cell motility protein 2
Gene Name Name: ELMO2
Organism Homo sapiens (Human)

DAG View
PRO Name engulfment and cell motility protein 2 (human)
Definition An engulfment and cell motility protein 2 that is encoded in the genome of human.
Short Label hELMO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q96JJ3 (ELMO2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S42 Phosphorylation PhosphoSitePlus
Y48 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107, 15951569
Y49 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
R320 Methylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
T387 Phosphorylation PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K415 Acetylation PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus   UniProt 23186163
S513 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K542 Ubiquitination PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K607 Ubiquitination PhosphoSitePlus
T611 Phosphorylation PhosphoSitePlus
K613 Ubiquitination PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
Y713 Phosphorylation PhosphoSitePlus   RLIMS-P 25332238
Y717 Phosphorylation PhosphoSitePlus
Y719 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y48 Phosphorylation HPRD 17016520, 15951569, 17389395
S328 Phosphorylation HPRD 20068231
S517 Phosphorylation HPRD 18077418
S711 Phosphorylation HPRD 20068231

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q96JJ3 (ELMO2) Y713 P30530 (AXL) unknown eFIP 25332238

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 L42 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
Y48 C48 Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y48 H48 Biomuta DOID:1909 / melanoma [ cosmic ]
S503 R503 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K600 I600 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]