iPTMnet Report for Q96JB5 (CDK5RAP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96JB5 / CK5P3_HUMAN
Protein Name CDK5 regulatory subunit-associated protein 3
Gene Name Name: CDK5RAP3
Synonyms:IC53;ORFNames:MSTP016,OK/SW-cl.114,PP1553;
Organism Homo sapiens (Human)

PRO ID PR:Q96JB5
DAG View
PRO Name CDK5 regulatory subunit-associated protein 3 (human)
Definition A CDK5 regulatory subunit-associated protein 3 that is encoded in the genome of human.
Short Label hCDK5RAP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96JB5 (CDK5RAP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K29 Ubiquitination PhosphoSitePlus
C68 Methylation IEDB 31844290
S81 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
C136 Methylation IEDB 31844290
Y143 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
R233 Methylation PhosphoSitePlus
Y239 Phosphorylation PhosphoSitePlus
Y346 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
K450 Sumoylation PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
Y494 Phosphorylation PhosphoSitePlus
T504 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S115 Phosphorylation HPRD 20068231
S116 Phosphorylation HPRD 20068231
T243 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 F81 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y110 H110 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C136 G136 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K146 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K166 R166 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R233 W233 Biomuta DOID:363 / uterine cancer [ icgc ]
K440 N440 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K442 M442 Biomuta DOID:3571 / liver cancer [ cosmic ]
K450 N450 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y494 C494 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T504 A504 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]