iPTMnet Report for Q96JB2 (COG3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96JB2 / COG3_HUMAN
Protein Name Conserved oligomeric Golgi complex subunit 3
Gene Name Name: COG3
Synonyms:SEC34;
Organism Homo sapiens (Human)

PRO ID PR:Q96JB2
DAG View
PRO Name conserved oligomeric Golgi complex subunit 3 (human)
Definition A conserved oligomeric Golgi complex subunit 3 that is encoded in the genome of human.
Short Label hCOG3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96JB2 (COG3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 12665801, 22223895, ...25944712
K21 Ubiquitination PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T93 O-Glycosylation GlyGen 34019948, 29237092, 29351928
K126 Acetylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
T273 Phosphorylation PhosphoSitePlus
T468 O-Glycosylation GlyGen 34019948, 29237092, 29351928
T477 O-Glycosylation GlyGen 34019948, 29237092, 29351928
S511 Phosphorylation PhosphoSitePlus
S514 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
T529 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
T604 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 19690332, ...20068231
K694 Ubiquitination PhosphoSitePlus
T717 Phosphorylation PhosphoSitePlus
K723 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K21 Q21 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S511 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S536 Y536 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S536 F536 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S636 F636 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]