iPTMnet Report for Q96J84 (KIRREL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96J84 / KIRR1_HUMAN
Protein Name Kin of IRRE-like protein 1 precursor
Gene Name Name: KIRREL1
Synonyms:KIRREL,NEPH1;
Organism Homo sapiens (Human)

PRO ID PR:Q96J84
DAG View
PRO Name kin of IRRE-like protein 1 (human)
Definition A kin of IRRE-like protein 1 that is encoded in the genome of human.
Short Label hKIRREL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96J84 (KIRREL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T31 Phosphorylation PhosphoSitePlus
N140 N-Glycosylation GlyGen 23090970, 24190977
N297 N-Glycosylation GlyGen   UniProt 23090970, 19159218, 24190977
K359 Acetylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
Y369 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
T563 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
Y572 Phosphorylation P06241 (FYN) neXtProt   PhosphoSitePlus 18258597
S573 Phosphorylation PhosphoSitePlus
S574 Phosphorylation PhosphoSitePlus   UniProt 23186163
K576 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
T592 Phosphorylation PhosphoSitePlus
Y596 Phosphorylation PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus
T602 Phosphorylation PhosphoSitePlus
Y605 Phosphorylation P06241 (FYN) neXtProt   PhosphoSitePlus   Signor 18258597
Y606 Phosphorylation P06241 (FYN) PhosphoSitePlus   Signor 18258597
Y622 Phosphorylation P06241 (FYN) neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18258597, 15144186
Y625 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15144186
R626 Methylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
Y647 Phosphorylation PhosphoSitePlus
T652 Phosphorylation PhosphoSitePlus
Y653 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
Y661 Phosphorylation PhosphoSitePlus
Y684 Phosphorylation PhosphoSitePlus
Y687 Phosphorylation PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
Y701 Phosphorylation PhosphoSitePlus
Y704 Phosphorylation PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
Y721 Phosphorylation PhosphoSitePlus
Y724 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15144186
K729 Ubiquitination PhosphoSitePlus
Y730 Phosphorylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
S737 Phosphorylation PhosphoSitePlus
Y738 Phosphorylation PhosphoSitePlus
T739 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S740 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S740 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
Y745 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S560 Phosphorylation HPRD 19007248
Y622 Phosphorylation HPRD 15144186
Y625 Phosphorylation HPRD 15144186
Y724 Phosphorylation HPRD 15144186


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S360 L360 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S552 C552 Biomuta DOID:3571 / liver cancer [ cosmic ]
K569 N569 Biomuta [ cosmic ]
S574 L574 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
K582 R582 Biomuta DOID:1324 / lung cancer [ cosmic ]
K599 M599 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y625 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
R626 H626 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
Y684 N684 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y724 C724 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y724 H724 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y738 C738 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S743 P743 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]