iPTMnet Report for Q96J01 (THOC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96J01 / THOC3_HUMAN
Protein Name THO complex subunit 3
Gene Name Name: THOC3
Organism Homo sapiens (Human)

PRO ID PR:Q96J01
DAG View
PRO Name THO complex subunit 3 (human)
Definition A THO complex subunit 3 that is encoded in the genome of human.
Short Label hTHOC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96J01 (THOC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
S28 Phosphorylation PhosphoSitePlus
R43 Methylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K77 Methylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
T123 O-Glycosylation GlyGen 34019948, 34229054, 30620550
R125 Methylation PhosphoSitePlus
R130 Methylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
C148 Methylation IEDB 31844290
T166 Phosphorylation PhosphoSitePlus
K171 Sumoylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
R264 Methylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
C306 Methylation IEDB 31844290
S308 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K332 Acetylation PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
K343 Sumoylation PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R125 H125 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K171 N171 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S335 I335 Biomuta DOID:9256 / colorectal cancer [ cosmic ]