iPTMnet Report for Q96IG2 (FBXL20)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96IG2 / FXL20_HUMAN
Protein Name F-box/LRR-repeat protein 20
Gene Name Name: FBXL20
Synonyms:FBL2;
Organism Homo sapiens (Human)

PRO ID PR:Q96IG2
DAG View
PRO Name F-box/LRR-repeat protein 20 (human)
Definition An F-box/LRR-repeat protein 20 that is encoded in the genome of human.
Short Label hFBXL20
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96IG2 (FBXL20) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
C220 Methylation IEDB 31844290
S251 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
T417 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 18669648, 23186163, ...24275569
S421 Phosphorylation PhosphoSitePlus   UniProt 23186163
S425 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T417 Phosphorylation HPRD 18578522, 18088087, 18669648, ...20230923
S421 Phosphorylation HPRD 20230923
S425 Phosphorylation HPRD 18578522, 20230923


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K10 N10 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K10 T10 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K140 M140 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K203 E203 Biomuta DOID:10283 / prostate cancer [ cosmic ]
C220 W220 Biomuta DOID:5041 / esophageal cancer [ cosmic ]