iPTMnet Report for Q96IF1 (AJUBA)
Protein Information
| UniProt AC / UniProt ID | Q96IF1 / AJUBA_HUMAN |
| Protein Name | LIM domain-containing protein ajuba |
| Gene Name | Name: AJUBA Synonyms:JUB; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96IF1 |
| PRO Name | LIM domain-containing protein ajuba (human) |
| Definition | A protein ajuba that is encoded in the genome of human. |
| Short Label | hAJUBA |
| Category | organism-gene |
Q96IF1 (AJUBA) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Phosphorylation | score1 | PRO | ||||
| K7 | Methylation | score1 | PhosphoSitePlus | |||
| K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T30 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S69 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S79 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163 | ||
| S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S119 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 18691976, 21406692, 23186163, ... | ||
| S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S126 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S133 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y169 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S175 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 27226586, 20068231 | ||
| Y215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S230 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S263 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T265 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K340 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y346 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S39 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S119 | Phosphorylation | score0 | HPRD | 18691976, 16964243, 20058876, ... | ||
| S136 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S137 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S175 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S196 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S237 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S263 | Phosphorylation | score0 | HPRD | 17081983 |
Proteoform PPIs
| Protein 1 | Relation | Protein 2 | Source | PMID | |
|---|---|---|---|---|---|
| PR:O60566 (hBUB1B) | Interaction | PR:Q96IF1 (hAJUBA) | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T30 | I30 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S69 | F69 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] | |
| S119 | G119 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S159 | R159 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| Y231 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K340 | R340 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View