Protein Information

Cytoscape View

UniProt AC / UniProt ID Q96I99 / SUCB2_HUMAN
Protein Name Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial precursor
Gene Name Name: SUCLG2
Organism Homo sapiens (Human)

DAG View
PRO Name succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (human)
Definition A succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial that is encoded in the genome of human.
Short Label hSUCLG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q96I99 (SUCLG2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
R91 Methylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
K132 Sumoylation PhosphoSitePlus
S149 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K218 Methylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus   UniProt 19608861
K291 Acetylation PhosphoSitePlus   UniProt 19608861
K338 Acetylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
K347 Acetylation PhosphoSitePlus
K423 Acetylation PhosphoSitePlus
K424 Acetylation PhosphoSitePlus
K431 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y153 Phosphorylation HPRD 20068231

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P20963 (CD247) Y72 Q96I99 (SUCLG2) unknown eFIP 24502978

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K132 E132 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
K338 N338 Biomuta DOID:3070 / malignant glioma [ tcga ]
K347 E347 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:5041 / esophageal cancer [ icgc ]
K424 N424 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]