iPTMnet Report for Q96I34 (PPP1R16A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96I34 / PP16A_HUMAN
Protein Name Protein phosphatase 1 regulatory subunit 16A precursor
Gene Name Name: PPP1R16A
Synonyms:MYPT3;
Organism Homo sapiens (Human)

PRO ID PR:Q96I34
DAG View
PRO Name protein phosphatase 1 regulatory subunit 16A (human)
Definition A protein phosphatase 1 regulatory subunit 16A that is encoded in the genome of human.
Short Label hPPP1R16A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96I34 (PPP1R16A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
T139 O-Glycosylation GlyGen 29351928
T188 Phosphorylation IEDB 35494241
S199 Phosphorylation PhosphoSitePlus
S353 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S418 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y434 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
K451 Acetylation PhosphoSitePlus
K460 Acetylation PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 R18 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T139 M139 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S418 F418 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S437 N437 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]