iPTMnet Report for Q96I24 (FUBP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96I24 / FUBP3_HUMAN
Protein Name Far upstream element-binding protein 3
Gene Name Name: FUBP3
Synonyms:FBP3;
Organism Homo sapiens (Human)

PRO ID PR:Q96I24
DAG View
PRO Name far upstream element-binding protein 3 (human)
Definition A far upstream element-binding protein 3 that is encoded in the genome of human.
Short Label hFUBP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96I24 (FUBP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22223895
K15 Acetylation PhosphoSitePlus
K15 Sumoylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K32 Acetylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
Y53 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K83 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
R95 Methylation PhosphoSitePlus
C109 Methylation IEDB 31844290
C109 S-Nitrosylation dbSNO 19483679
T130 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
R147 Methylation PhosphoSitePlus
R149 Methylation PhosphoSitePlus
S162 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
S172 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
R180 Methylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
R241 Methylation PhosphoSitePlus
R244 Methylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
R286 Methylation PhosphoSitePlus
S296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 23186163, 18669648, ...24275569, 20068231
R299 Methylation PhosphoSitePlus
R309 Methylation PhosphoSitePlus
R337 Methylation PhosphoSitePlus
R339 Methylation PhosphoSitePlus
R341 Methylation PhosphoSitePlus
R343 Methylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
T358 Phosphorylation PhosphoSitePlus
Y359 Phosphorylation PhosphoSitePlus
T360 Phosphorylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
R408 Methylation PhosphoSitePlus
T428 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
S439 Phosphorylation PhosphoSitePlus
S442 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
S442 Phosphorylation PhosphoSitePlus
S457 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
S457 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus
K518 Sumoylation PhosphoSitePlus
Y523 Phosphorylation PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus
S532 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
S532 Phosphorylation PhosphoSitePlus
S538 Phosphorylation phospho.ELM 18669648
S539 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
Y543 Phosphorylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
Y550 Phosphorylation PhosphoSitePlus
S569 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...35138101, 34019948, 34725712, 30059200, 29351928, 35132862, 35083852, 31492838, 32119511, 35289036, 35254053, 22121020, 34229054, 29237092
S569 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 19690332, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
T76 Phosphorylation HPRD 20068231
S296 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S532 Phosphorylation HPRD 17081983
S538 Phosphorylation HPRD 18669648
S539 Phosphorylation HPRD 19651622, 18669648, 20068231
Y543 Phosphorylation HPRD 17081983
Y551 Phosphorylation HPRD 17081983
S569 Phosphorylation HPRD 17525332, 18077418, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 F42 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S49 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S49 L49 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
Y53 C53 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R95 S95 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R147 C147 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
R147 H147 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R149 Q149 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
R149 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R241 Q241 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R241 W241 Biomuta DOID:4159 / skin cancer [ cosmic ]
S259 Y259 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S259 F259 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K278 N278 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K278 R278 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S296 I296 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R309 Q309 Biomuta [ cosmic ]
R309 W309 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R341 C341 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
R343 H343 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y359 C359 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T360 M360 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T428 I428 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S442 N442 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S458 F458 Biomuta DOID:4159 / skin cancer [ cosmic ]
S539 T539 Biomuta DOID:4159 / skin cancer [ cosmic ]
S539 Y539 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S539 F539 Biomuta DOID:4159 / skin cancer [ cosmic ]