iPTMnet Report for Q96HY7 (DHTKD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HY7 / DHTK1_HUMAN
Protein Name 2-oxoadipate dehydrogenase complex component E1 precursor
Gene Name Name: DHTKD1
Synonyms:KIAA1630;
Organism Homo sapiens (Human)

PRO ID PR:Q96HY7
DAG View
PRO Name 2-oxoadipate dehydrogenase complex component E1 (human)
Definition A 2-oxoadipate dehydrogenase complex component E1 that is encoded in the genome of human.
Short Label hDHTKD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HY7 (DHTKD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C64 Methylation IEDB 31844290
K148 Acetylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
K553 Ubiquitination PhosphoSitePlus
S795 Phosphorylation HPRD 20068231
S796 Phosphorylation HPRD 20068231
K800 Acetylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
K818 Acetylation PhosphoSitePlus
K827 Acetylation PhosphoSitePlus
K881 Ubiquitination PhosphoSitePlus
K886 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K148 R148 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T157 M157 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K800 R800 Biomuta DOID:3571 / liver cancer [ cosmic ]