Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HW7 / INT4_HUMAN
Protein Name Integrator complex subunit 4
Gene Name Name: INTS4
ORFNames:MSTP093;
Organism Homo sapiens (Human)

PRO ID PR:Q96HW7
DAG View
PRO Name integrator complex subunit 4 (human)
Definition An integrator complex subunit 4 that is encoded in the genome of human.
Short Label hINTS4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HW7 (INTS4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y10 Phosphorylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
K677 Ubiquitination PhosphoSitePlus
Y686 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
T737 Phosphorylation PhosphoSitePlus
T740 Phosphorylation PhosphoSitePlus
T741 Phosphorylation PhosphoSitePlus
K791 Sumoylation PhosphoSitePlus
T801 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S617 Phosphorylation HPRD 20068231
Y686 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
T4 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K27 R27 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
K169 T169 Biomuta DOID:363 / uterine cancer [ tcga ]
K228 T228 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S292 N292 Biomuta DOID:10534 / stomach cancer [ tcga ]
S600 C600 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K698 T698 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T740 I740 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]