iPTMnet Report for Q96HW7 (INTS4)
Protein Information
| UniProt AC / UniProt ID | Q96HW7 / INT4_HUMAN |
| Protein Name | Integrator complex subunit 4 |
| Gene Name | Name: INTS4 ORFNames:MSTP093; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96HW7 |
| PRO Name | integrator complex subunit 4 (human) |
| Definition | An integrator complex subunit 4 that is encoded in the genome of human. |
| Short Label | hINTS4 |
| Category | organism-gene |
Q96HW7 (INTS4) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T25 | O-Glycosylation | score1 | GlyGen | 30379171, 31492838, 34019948 | ||
| K26 | Acetylation | score1 | PhosphoSitePlus | |||
| K26 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K27 | Acetylation | score1 | PhosphoSitePlus | |||
| K62 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K228 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S242 | O-Glycosylation | score1 | GlyGen | 30379171, 31492838, 34019948 | ||
| Y245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K340 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K495 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S600 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S617 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S660 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K677 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y686 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K688 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K698 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T737 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T740 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T741 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K791 | Sumoylation | score1 | PhosphoSitePlus | |||
| T801 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S935 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S617 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y686 | Phosphorylation | score0 | HPRD | 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S5 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K27 | R27 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| K169 | T169 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K228 | T228 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S292 | N292 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S600 | C600 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S617 | N617 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K698 | T698 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T740 | I740 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View