iPTMnet Report for Q96HR8 (NAF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HR8 / NAF1_HUMAN
Protein Name H/ACA ribonucleoprotein complex non-core subunit NAF1
Gene Name Name: NAF1
Organism Homo sapiens (Human)

PRO ID PR:Q96HR8
DAG View
PRO Name H/ACA ribonucleoprotein complex non-core subunit NAF1 (human)
Definition An H/ACA ribonucleoprotein complex non-core subunit NAF1 that is encoded in the genome of human.
Short Label hNAF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HR8 (NAF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S110 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K167 Sumoylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...20068231
S329 Phosphorylation PhosphoSitePlus
K338 Sumoylation PhosphoSitePlus
R375 Methylation PhosphoSitePlus
R379 Methylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
R384 Methylation PhosphoSitePlus
R389 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S315 Phosphorylation HPRD 19413330, 18767875, 19664994, ...18452278, 19651622, 15302935, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S139 L139 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S141 P141 Biomuta DOID:4362 / cervical cancer [ icgc ]
S142 C142 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S329 Y329 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R375 Q375 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
R375 * Biomuta DOID:1319 / brain cancer [ cosmic ]
R389 T389 Biomuta DOID:9256 / colorectal cancer [ cosmic ]