iPTMnet Report for Q96HP0 (DOCK6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HP0 / DOCK6_HUMAN
Protein Name Dedicator of cytokinesis protein 6
Gene Name Name: DOCK6
Synonyms:KIAA1395;
Organism Homo sapiens (Human)

PRO ID PR:Q96HP0
DAG View
PRO Name dedicator of cytokinesis protein 6 (human)
Definition A dedicator of cytokinesis protein 6 that is encoded in the genome of human.
Short Label hDOCK6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HP0 (DOCK6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S40 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S41 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T48 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S176 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
S185 O-Glycosylation GlyGen 35254053
S185 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
T397 Phosphorylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
T636 Phosphorylation PhosphoSitePlus
S749 Phosphorylation PhosphoSitePlus
R865 Methylation PhosphoSitePlus
S872 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y874 Phosphorylation PhosphoSitePlus
S878 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K879 Ubiquitination PhosphoSitePlus
S880 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S882 Phosphorylation PhosphoSitePlus
S883 Phosphorylation PhosphoSitePlus
S884 Phosphorylation PhosphoSitePlus
S941 Phosphorylation HPRD   PhosphoSitePlus 19413330
S1190 Phosphorylation PhosphoSitePlus
S1194 Phosphorylation P31749 (AKT1) PhosphoSitePlus 23462102
S1230 Phosphorylation PhosphoSitePlus
T1237 Phosphorylation HPRD   PhosphoSitePlus 17924679
S1239 Phosphorylation HPRD   PhosphoSitePlus 17924679
S1246 Phosphorylation PhosphoSitePlus
S1308 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K1318 Acetylation PhosphoSitePlus
K1318 Methylation PhosphoSitePlus
S1343 Phosphorylation PhosphoSitePlus
S1356 Phosphorylation PhosphoSitePlus
K1371 Methylation PhosphoSitePlus
T1679 Phosphorylation PhosphoSitePlus
K1871 Acetylation PhosphoSitePlus
T2029 Phosphorylation PhosphoSitePlus
S2036 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2041 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 F35 Biomuta DOID:4159 / skin cancer [ cosmic ]
S42 F42 Biomuta [ cosmic ]
S159 F159 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T397 M397 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
R865 H865 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R865 C865 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K879 N879 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T1237 M1237 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1356 G1356 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1871 N1871 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]