Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HH9 / GRM2B_HUMAN
Protein Name GRAM domain-containing protein 2B
Gene Name Name: GRAMD2B
Synonyms:GRAMD3,NS3TP2;
Organism Homo sapiens (Human)

PRO ID PR:Q96HH9
DAG View
PRO Name GRAM domain-containing protein 2B (human)
Definition A GRAM domain-containing protein 2B that is encoded in the genome of human.
Short Label hGRAMD2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HH9 (GRAMD2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S29 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
S230 Phosphorylation PhosphoSitePlus
S252 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231, ...18220336
S273 Phosphorylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
T287 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T95 Phosphorylation HPRD 20068231
Y106 Phosphorylation HPRD 20068231
Y195 Phosphorylation HPRD 19664994
S205 Phosphorylation HPRD 20068231
Y207 Phosphorylation HPRD 20068231
S212 Phosphorylation HPRD 17081983
T220 Phosphorylation HPRD 17081983
S221 Phosphorylation HPRD 17081983
S234 Phosphorylation HPRD 17081983
S252 Phosphorylation HPRD 19651622, 18669648, 20068231
S296 Phosphorylation HPRD 20068231
S319 Phosphorylation HPRD 18452278
S326 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S44 L44 Biomuta DOID:4159 / skin cancer [ icgc ]
S49 P49 Biomuta DOID:363 / uterine cancer [ tcga ]
S53 F53 Biomuta DOID:1324 / lung cancer [ tcga ]
S212 F212 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:10534 / stomach cancer [ icgc ]
S212 A212 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T220 A220 Biomuta DOID:363 / uterine cancer [ tcga ]
S252 * Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S273 A273 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S273 C273 Biomuta DOID:1324 / lung cancer [ cosmic ]
S326 * Biomuta DOID:5041 / esophageal cancer [ tcga ]