iPTMnet Report for Q96HA7 (TONSL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HA7 / TONSL_HUMAN
Protein Name Tonsoku-like protein
Gene Name Name: TONSL
Synonyms:IKBR;
Organism Homo sapiens (Human)

PRO ID PR:Q96HA7
DAG View
PRO Name tonsoku-like protein (human)
Definition A tonsoku-like protein that is encoded in the genome of human.
Short Label hTONSL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HA7 (TONSL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 O-Glycosylation GlyGen 30379171, 30620550, 35254053
C124 Methylation IEDB 31844290
C181 Methylation IEDB 31844290
K187 Ubiquitination PhosphoSitePlus
C224 Methylation IEDB 31844290
K275 Ubiquitination PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
C413 Methylation IEDB 31844290
K416 Ubiquitination PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
K643 Ubiquitination PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163, 20068231
S739 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
R797 Methylation PhosphoSitePlus
R812 Methylation PhosphoSitePlus
S860 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
S888 Phosphorylation PhosphoSitePlus
S900 Phosphorylation PhosphoSitePlus
S905 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
T908 Phosphorylation PhosphoSitePlus
S912 O-Glycosylation GlyGen 30379171, 32938750, 30620550, ...35254053
T1070 Phosphorylation PhosphoSitePlus
C1156 Methylation IEDB 31844290
K1263 Ubiquitination PhosphoSitePlus
C1275 Methylation IEDB 31844290
K1329 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S719 Phosphorylation HPRD 18691976, 20068231
S907 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 G2 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S2 I2 Biomuta DOID:4159 / skin cancer [ cosmic ]
K336 M336 Biomuta DOID:263 / kidney cancer [ cosmic ]
S719 Y719 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R797 Q797 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:8618 / oral cavity cancer [ cosmic ]
R812 Q812 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S863 Y863 Biomuta DOID:363 / uterine cancer [ icgc ]
C1275 Y1275 Biomuta DOID:1319 / brain cancer [ cosmic ]