iPTMnet Report for Q96HA1 (POM121)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HA1 / P121A_HUMAN
Protein Name Nuclear envelope pore membrane protein POM 121
Gene Name Name: POM121
Synonyms:KIAA0618,NUP121,POM121A;
Organism Homo sapiens (Human)

PRO ID PR:Q96HA1
DAG View
PRO Name nuclear envelope pore membrane protein POM 121 (human)
Definition A nuclear envelope pore membrane protein POM 121 that is encoded in the genome of human.
Short Label hPOM121
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HA1 (POM121) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
R183 Methylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
R215 Methylation PhosphoSitePlus
R223 Methylation PhosphoSitePlus
R229 Methylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
R265 Methylation PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S298 Phosphorylation PhosphoSitePlus
K309 Ubiquitination PhosphoSitePlus
T311 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
K317 Acetylation PhosphoSitePlus
K317 Ubiquitination PhosphoSitePlus
K319 Acetylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus   UniProt 18669648
S371 Phosphorylation PhosphoSitePlus   UniProt 21406692
S378 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
Y417 Phosphorylation PhosphoSitePlus
S424 Phosphorylation PhosphoSitePlus
K428 Methylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
S434 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
T485 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
T497 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
T565 O-Glycosylation GlyGen 32938750
S626 Phosphorylation PhosphoSitePlus
S632 O-Glycosylation GlyGen 33214551, 34019948, 35254053, ...35132862, 31492838, 35289036, 30620550
S640 O-Glycosylation GlyGen 33214551, 34019948, 35254053, ...35132862, 31492838, 35289036, 30620550
T660 O-Glycosylation GlyGen 29351928
T688 O-Glycosylation GlyGen 33214551, 32938750, 34019948, ...30620550, 35132862, 31492838, 35289036, 35254053
K689 Ubiquitination PhosphoSitePlus
T693 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 34019948, 32938750, ...30059200, 30620550, 35132862, 31492838, 35289036, 35254053, 20068230
S694 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 34019948, 32938750, ...30059200, 30620550, 35132862, 31492838, 35289036, 35254053, 20068230
S697 O-Glycosylation GlyGen 33214551, 34019948, 35254053, ...35132862, 31492838, 35289036, 30620550
S697 Phosphorylation PhosphoSitePlus
T711 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S714 Phosphorylation PhosphoSitePlus
S715 Phosphorylation PhosphoSitePlus
S722 O-Glycosylation GlyGen 33214551, 34019948, 35254053, ...35132862, 31492838, 35289036, 30620550
T733 O-Glycosylation GlyGen 33214551, 34019948, 30059200, ...35254053, 35132862, 31492838, 35289036, 30620550
K737 Acetylation PhosphoSitePlus
S738 O-Glycosylation GlyGen   PhosphoSitePlus 33214551, 30059200, 35132862, ...30620550, 34019948, 31492838, 35289036, 35254053, 20068230
S941 O-Glycosylation GlyGen 29351928
T945 Phosphorylation PhosphoSitePlus
T947 O-Glycosylation GlyGen 29351928
S954 O-Glycosylation GlyGen 29351928
S955 O-Glycosylation GlyGen 29351928
S958 O-Glycosylation GlyGen 29351928
S958 Phosphorylation PhosphoSitePlus
S962 O-Glycosylation GlyGen 29351928
T996 O-Glycosylation GlyGen 33214551, 34019948, 35254053, ...35132862, 31492838, 35289036, 30620550
S1000 O-Glycosylation GlyGen 33214551, 34019948, 35254053, ...35132862, 31492838, 35289036, 30620550
T1024 Phosphorylation PhosphoSitePlus
S1052 O-Glycosylation GlyGen 29351928
S1053 O-Glycosylation GlyGen 29351928
T1168 O-Glycosylation GlyGen 29351928
T1169 O-Glycosylation GlyGen 29351928
S1171 O-Glycosylation GlyGen 29351928
T1246 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation HPRD 18669648, 19691289
S33 Phosphorylation HPRD 18669648
S35 Phosphorylation HPRD 18669648
S36 Phosphorylation HPRD 18669648
T46 Phosphorylation HPRD 19413330
S49 Phosphorylation HPRD 18669648, 20068231
S80 Phosphorylation HPRD 19651622, 18669648, 20068231
S81 Phosphorylation HPRD 18669648, 17081983, 20068231
S83 Phosphorylation HPRD 18669648, 17081983, 20068231
S86 Phosphorylation HPRD 19651622, 18669648, 17081983
S115 Phosphorylation HPRD 17081983
S116 Phosphorylation HPRD 19651622
S124 Phosphorylation HPRD 17081983
S127 Phosphorylation HPRD 18669648
S128 Phosphorylation HPRD 18669648
S130 Phosphorylation HPRD 18669648
S131 Phosphorylation HPRD 18669648
Y136 Phosphorylation HPRD 17081983
S138 Phosphorylation HPRD 20068231
S142 Phosphorylation HPRD 17081983
S143 Phosphorylation HPRD 18669648, 17081983, 20068231
S144 Phosphorylation HPRD 18669648, 17081983
T149 Phosphorylation HPRD 18669648
S154 Phosphorylation HPRD 18669648
S168 Phosphorylation HPRD 20068231
S170 Phosphorylation HPRD 18669648, 19691289, 20068231
S173 Phosphorylation HPRD 20068231
S174 Phosphorylation HPRD 18669648, 20068231
S178 Phosphorylation HPRD 20068231
S229 Phosphorylation HPRD 18077418
S231 Phosphorylation HPRD 18077418
S235 Phosphorylation HPRD 18077418
S432 Phosphorylation HPRD 19413330, 18669648
S450 Phosphorylation HPRD 19413330, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T46 I46 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S49 N49 Biomuta DOID:1324 / lung cancer [ cosmic ]
S116 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S124 F124 Biomuta DOID:4159 / skin cancer [ cosmic ]
S127 F127 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S128 F128 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S174 P174 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R183 P183 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S184 P184 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S188 C188 Biomuta [ cosmic ]
S188 P188 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R223 W223 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R265 M265 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T311 I311 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S314 N314 Biomuta DOID:1324 / lung cancer [ cosmic ]
S381 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S389 F389 Biomuta DOID:4159 / skin cancer [ cosmic ]
S392 F392 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S393 F393 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T398 R398 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S464 Y464 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S464 F464 Biomuta DOID:4159 / skin cancer [ cosmic ]
S632 N632 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
S694 C694 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T711 A711 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S714 P714 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
S722 Y722 Biomuta DOID:363 / uterine cancer [ icgc ]
T733 A733 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]