iPTMnet Report for Q96H40 (ZNF486)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96H40 / ZN486_HUMAN
Protein Name Zinc finger protein 486
Gene Name Name: ZNF486
Synonyms:KRBO2;
Organism Homo sapiens (Human)

PRO ID PR:Q96H40
DAG View
PRO Name zinc finger protein 486 (human)
Definition A zinc finger protein 486 that is encoded in the genome of human.
Short Label hZNF486
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96H40 (ZNF486) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K211 Sumoylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K239 Sumoylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
T289 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
K342 Acetylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K351 Sumoylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K357 Acetylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K379 Acetylation PhosphoSitePlus
K379 Sumoylation PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
T399 Phosphorylation PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K407 Sumoylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
T429 Phosphorylation PhosphoSitePlus
K432 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K239 N239 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K239 I239 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S252 N252 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T255 A255 Biomuta DOID:3571 / liver cancer [ cosmic ]
S261 T261 Biomuta DOID:3571 / liver cancer [ cosmic ]
S261 C261 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T317 I317 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K342 Q342 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T345 K345 Biomuta DOID:3571 / liver cancer [ cosmic ]
T345 M345 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K351 N351 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K369 N369 Biomuta DOID:4159 / skin cancer [ cosmic ]
T373 I373 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T399 I399 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K404 R404 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T429 P429 Biomuta DOID:4159 / skin cancer [ cosmic ]