iPTMnet Report for Q96GV9 (MACIR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96GV9 / MACIR_HUMAN
Protein Name Macrophage immunometabolism regulator
Gene Name Name: MACIR
Synonyms:C5orf30;
Organism Homo sapiens (Human)

PRO ID PR:Q96GV9
DAG View
PRO Name macrophage immunometabolism regulator (human)
Definition A macrophage immunometabolism regulator that is encoded in the genome of human.
Short Label hMACIR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96GV9 (MACIR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S25 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 19664994, ...19651622, 20068231
S37 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
T39 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
T47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
R112 Methylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y143 Phosphorylation PhosphoSitePlus
C156 Methylation IEDB 31844290
K166 Ubiquitination PhosphoSitePlus
S167 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 19664994, ...19651622, 18669648, 20068231
Y170 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T47 N47 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S49 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S140 P140 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K166 T166 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S167 Y167 Biomuta DOID:9256 / colorectal cancer [ cosmic ]