iPTMnet Report for Q96GJ1 (TRMT2B)
Protein Information
| UniProt AC / UniProt ID | Q96GJ1 / TRM2B_HUMAN |
| Protein Name | tRNA (uracil-5-)-methyltransferase homolog B precursor |
| Gene Name | Name: TRMT2B Synonyms:CXorf34; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96GJ1 |
| PRO Name | tRNA (uracil-5-)-methyltransferase homolog B (human) |
| Definition | A tRNA (uracil-5-)-methyltransferase that is encoded in the genome of human. |
| Short Label | hTRMT2B |
| Category | organism-gene |
DAG ViewQ96GJ1 (TRMT2B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T89 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T233 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K259 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K263 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y333 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K403 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K410 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K412 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y96 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K263 | N263 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| K412 | N412 | Biomuta | DOID:1319 / brain cancer [ icgc ] |
