iPTMnet Report for Q96G46 (DUS3L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96G46 / DUS3L_HUMAN
Protein Name tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like
Gene Name Name: DUS3L
Organism Homo sapiens (Human)

PRO ID PR:Q96G46
DAG View
PRO Name tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (human)
Definition A tRNA-dihydrouridine synthase 3-like that is encoded in the genome of human.
Short Label hDUS3L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96G46 (DUS3L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
K38 Ubiquitination PhosphoSitePlus
K48 Acetylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
S236 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
T240 Phosphorylation PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
T273 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
S276 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S277 Phosphorylation PhosphoSitePlus
T281 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
K354 Methylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S543 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
Y610 Phosphorylation PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S236 Phosphorylation HPRD 18669648, 20068231
T240 Phosphorylation HPRD 20068231
T271 Phosphorylation HPRD 17081983
S272 Phosphorylation HPRD 20068231
T273 Phosphorylation HPRD 19413330, 19651622, 18669648, ...17081983, 19664995
S276 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S277 Phosphorylation HPRD 19413330, 19664995, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K120 N120 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S236 N236 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K403 N403 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S543 L543 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]