Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96G23 / CERS2_HUMAN
Protein Name Ceramide synthase 2
Gene Name Name: CERS2
Synonyms:LASS2,TMSG1;
Organism Homo sapiens (Human)

PRO ID PR:Q96G23
DAG View
PRO Name ceramide synthase 2 (human)
Definition A ceramide synthase 2 that is encoded in the genome of human.
Short Label hCERS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96G23 (CERS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N19 N-Glycosylation UniProt 16263699, 19159218
Y88 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K334 Acetylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
S341 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 18088087, ...17081983, 19691289, 19007248, 19651622, 18669648, 20166139, 18318008, 19415658, 20068231
T346 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 18088087, ...17081983, 18318008, 19651622, 18669648, 20166139, 19415658, 20068231
S348 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 18088087, ...17081983, 18318008, 19651622, 18669648, 20166139, 19415658, 20068231
S349 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 18088087, ...17081983, 18318008, 19651622, 18669648, 20166139, 23186163, 19415658, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y88 C88 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K93 N93 Biomuta DOID:1319 / brain cancer [ icgc ]