iPTMnet Report for Q96FZ2 (HMCES)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96FZ2 / HMCES_HUMAN
Protein Name Abasic site processing protein HMCES
Gene Name Name: HMCES
Synonyms:C3orf37;
Organism Homo sapiens (Human)

PRO ID PR:Q96FZ2
DAG View
PRO Name abasic site processing protein HMCES (human)
Definition An abasic site processing protein HMCES that is encoded in the genome of human.
Short Label hHMCES
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96FZ2 (HMCES) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Ubiquitination PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K89 Sumoylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K148 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
S160 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163
K166 Ubiquitination PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
K275 Sumoylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus   UniProt 23186163
S301 Phosphorylation PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
K306 Sumoylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
S322 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K327 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
K339 Sumoylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K342 Sumoylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K44 N44 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S88 F88 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K166 Q166 Biomuta DOID:363 / uterine cancer [ icgc ]
T263 S263 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S301 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S309 L309 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S315 Y315 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K349 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]