iPTMnet Report for Q96FX7 (TRMT61A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96FX7 / TRM61_HUMAN
Protein Name tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A
Gene Name Name: TRMT61A
Synonyms:C14orf172,TRM61;
Organism Homo sapiens (Human)

PRO ID PR:Q96FX7
DAG View
PRO Name tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A (human)
Definition A tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A that is encoded in the genome of human.
Short Label hTRMT61A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96FX7 (TRMT61A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22223895
S2 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
R32 Methylation PhosphoSitePlus
S46 Phosphorylation PhosphoSitePlus
K57 Acetylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
R62 Methylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus   UniProt 19690332
S267 Phosphorylation PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R32 C32 Biomuta DOID:4362 / cervical cancer [ icgc ]
R62 * Biomuta DOID:1319 / brain cancer [ cosmic ]
T269 M269 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]